Are you talking about for Joystick Throttle control? If so what you need to set if you have a single throttle is the Power Half Axis and Brake Half Axis setting. Set one to the Positive Axis and the other to the Negative Axis. If you are lucky enough to have 2 separate throttles, you would use the Power Full Axis on one and the Brake Full Axis on the other. Edit: I should have added, you need to set Single Full Axis also for trains with a single control like the R160's.